QUANTITATION OF A NOVEL ENGINEERED ANTI-INFECTIVE HOST DEFENSE PEPTIDE, ARV-1502: PHARMACOKINETIC STUDY OF DIFFERENT DOSES IN RATS AND DOGS

The designer Powders proline-rich antimicrobial peptide (PrAMP) Chex1-Arg20 amide (ARV-1502) is active against Gram-negative and Gram-positive pathogens in different murine infection models when administered parenterally and possesses a wide therapeutic index.Here we studied the pharmacokinetics of ARV-1502 for the first time when administered intr

This study identified the relationship between preoccupation with devotional songs and spiritual well-being of religious individuals, and examined the mediating effect of intrinsic religiosity on preoccupation with devotional songs and spiritual well-being, moderated by the emotionally adaptive functions of music.The participants were 427 male and